Which of the following medications is considered unsafe while driving?

Morphine, an opioid analgesic, is considered unsafe while driving due to its sedative effects and potential for impairing cognitive and motor functions. Opioids like morphine can lead to drowsiness, confusion, and decreased reaction times, creating a significant risk for individuals operating vehicles. These effects can jeopardize the safety of the driver and others on the road.

In contrast, medications such as ibuprofen, acetaminophen, and aspirin are generally considered safer for driving as they do not usually cause sedation or impair cognitive functions to a degree that would affect driving ability. While taking any medication should be approached with caution, morphine's specific profile makes it particularly concerning when combined with activities that require full concentration and alertness, such as driving.